Dragon's blood, a deep red resin derived from Tree Sap, is a well-known traditional tonic, obtained from four different sources: Croton spp. (syn. Sangre de draco, Euphorbiaceae), Dracaena spp. (syn. Zanzibar drop, Dracaenaceae), Daemonorops spp. (syn. Jerang or Djerang, Palmaceae), and Pterocarpus spp. (syn. East India Kino or Malabar Kino, Fabaceae).

Dragon's blood has been used by different civilizations such as the Greeks, the Romans, and the Arabs

Here are some of the documented studies on Dragons Blood:

Croton lechleri has several medicinal properties, such as 

• wound healing 1, 2
• formation of skin cells 3
• immunomodulator 1, 4
• analgesic, antiulcer, antidiarrheal 1
• antibacterial 5
• antiviral 6
• antihemorrhagic 1
• anti-inflammatory, antioxidant 1, 3 
• mutagenic and antimutagenic 1, 3, 7 
• antitumor 1, 8 
• may help with cancer 9 

Proanthocyanidins are the main chemical constituent of the resin, >90% of the dry weight 10

It also contains taspin, an alkaloid, and catechin, epigalocatechin, epicatechin, and a small percentage of terpene compounds 11, 12

Wounds, the physical damage to the skin and its underlying structure, can result from trauma, burns, or chemicals.13 Wound healing is a complicated process. According to cellular and molecular mechanisms, there are three overlapping phases of wound healing as follows: inflammation due to the migration of fibroblasts and inflammatory cells, such as neutrophils and monocytes, into the wound site; then, reconstruction of the epithelial barrier and production matrix at the site of injury leading to new tissue formation; and finally, maturation 14, 15, 16

Dragon's blood has the immunomodulatory property by influence on complement system.4 The antioxidant agents from Dragon's blood leaves and fruit, such as phenolic profile and organic acids, are able to protect against free radicals 17, 18

Noteworthy, the anti-inflammatory effect of the alkaloid taspine has been reported.19 These studies have shown this plant can promote healing by affecting the inflammatory phase. Studies confirm that after only 1 day of treatment with Dragon's blood, the wound contracts and a dark crust forms on the wound surface which prevents secondary infection 2, 20

It also stimulates the proliferation and migration of fibroblasts and the production of collagen, resulting in epithelial regeneration and wound healing which can affect second and third phases of the healing process 2, 12

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